Drugs to Treat Hepatitis Archives - Beacon Pharmaceuticals PLC

Peginterferon alfa 2a (Pegin)

Product Description: Pegylated interferon alfa-2a is an antiviral drug, has a dual mode of action - both antiviral and on the immune system. The addition of polyethylene glycol to the interferon, through a process known as pegylation, enhances the half-life of the interferon when compared to its native form

Product Description:

Product Name	: Pegin
Generic Name	: Peginterferon alfa 2a
Formulation	: Prefilled Injection
Available Pack Size	: 1's
Available Strengths	: 135mg and 180mg
Registrations	: Bangladesh, Myanmar

Details

Ribavirin (Copeg)

Product Description: Ribavirin is an anti-viral drug indicated for severe RSV infection (individually), Hepatitis C infection (used in conjunction with Peginterferon) and other viral infections. Ribavirin is a prodrug, which when metabolized resembles purine RNA nucleotides. In this form it interferes with RNA metabolism required for viral replication. How it exactly affects viral replication is unknown; many mechanisms have been proposed for this but none of these has been proven to date. Multiple mechanisms may be responsible for its actions.

Product Features:

Product Name	: Copeg
Generic Name	: Ribavirin
Formulation	: Tablet
Available Pack Size	: 20's
Available Strengths	: 200 mg
Registrations	: Bangladesh, Myanmar

Details

Sofosbuvir (Soforal)

Product Description: Sofosbuvir directly targets the Hepatitis C virus to stop it from making copies of itself in the liver. Sofosbuvir attaches itself to the genetic information, called RNA, to block the virus from multiplying.

Product Features:

Product Name	: Soforal
Generic Name	: Sofosbuvir
Formulation	: Tablet
Available Pack Size	: 8's
Available Strengths	: 400 mg
Registrations	: Bangladesh

Details

Daclatasvir (Daclavir)

Product Description: Daclavir (Daclatasvir) is one of the new direct-acting antiviral drugs that target different steps of the hepatitis C virus (HCV) lifecycle. It is the first-ever approved HCV NS5A replication complex inhibitor, meaning it interferes with a protein the virus uses to reproduce.

Product Features:

Product Name	:	Daclavir
Generic Name	:	Daclatasvir
Formulation	:	Tablet
Available Pack Size	:	1x10’s
Available Strength	:	60 mg
Registrations	:	Bangladesh

Details

Tenofovir Disoproxil Fumarate 300mg (Becovir)

Product Description: TENOFOVIR is an antiretroviral agent, which belongs to a class of drugs called “nucleotide reverse transcriptase inhibitor” or “NtRTI.” TENOFOVIR mimics a nucleoside base, which blocks further construction of the virus. When combined with other antiretroviral agents, TENOFOVIR can achieve a significant decrease in viral multiplication.

Product Features:

Product Name	:	Becovir
Generic Name	:	Tenofovir Disoproxil Fumarate
Formulation	:	Tablet
Available Pack Size	:	1x8’s
Available Strength	:	300 mg
Registrations	:	Bangladesh

Details

Entecavir 0.5 mg (Caviral)

Product Description: Entecavir is a guanosine analogue with marked activity against HBV DNA polymerase. It is licensed for the treatment of chronic Hepatitis B virus infection in patients with compensated liver disease and evidence of acute viral replication, persistently elevated serum alanine aminotransferase levels and histological evidence of active inflammation and/or fibrosis.

Product Features:

Product Name	:	Caviral
Generic Name	:	Entecavir
Formulation	:	Tablet
Available Pack Size	:	1x10’s
Available Strength	:	0.5 mg
Registrations	:	Bangladesh

Details

Sofosbuvir+Velpatasvir (Sofosvel)

Sofosvel is the global first generic oral tablet for pan-genotypic Chronic Hepatitis C treatment. This combination (Sofosbuvir 400 mg + Valpatasvir 100 mg) drug has been approved by US FDA & European Commission for treatment of patients with all genotypic Chronic Hepatitis C virus infection. Sofosvel is used without cirrhosis or with compensated cirrhosis, and patients with advanced cirrhosis (Decompensated).

Therapeutic indications:

Sofosvel is indicated for the treatment of adult patients with chronic hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5 or 6 infections

With or without cirrhosis or with compensated cirrhosis
With decompensated cirrhosis for use in combination with Ribavirin

Product Name : Sofosvel

Generic Name : Sofosbuvir 400mg + Velpatasvir 100 mg

Formulation : Solid dosage form(Tablet)

Available pack size : 1×6’s

Strengths : 400mg+ 100mg

Details

Sofosbuvir 400mg + Ledipasvir 90 mg

Product Description: Soforal LP is a fixed –dose combination tablet containing Ledipasvir and Sofosbuvir for oral administration.

Product Features:

Soforal LP is a fixed-dose combination of Ledipasvir, a hepatitis C virus (HCV) NS5A inhibitor, and Sofosbuvir, an HCV nucleotide analog NS5B polymerase inhibitor, and is indicated for the treatment of chronic hepatitis C virus (HCV) in: A. Adults with genotype 1, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis B. Adults with genotype 1 infection with decompensate cirrhosis, in combination with Ribavirin C. Adults with genotype 1 or 4 infection who are liver transplant recipients without cirrhosis or with compensated cirrhosis, in combination with Ribavirin.


Product Name	: Soforal LP
Generic Name	: Sofosbuvir + Ledipasvir
Formulation	: Tablet
Available Pack Size	: 6’s
Available Strength	: 400 mg + 90 mg
Registrations	: Bangladesh

Details