General Products

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  • Product Description:

    Xalcort is a preparation of Deflazacort INN which is an oxazolone derivative of prednisolone, possess similar effect like prednisolone but relatively fewer side effects than prednisolone. Deflazacort provides anti-inflammatory action by inhibiting Phospholipase A2 enzyme which is responsible for prostaglandin synthesis. Besides Deflazacort decreases the release of certain chemicals that are important in the immune system. By decreasing the release of these chemicals, Deflazacort provides immunosuppressive action.

    Deflazacort is indicated for rheumatoid arthritis, juvenile chronic arthritis, asthma and other airway diseases, pemphigus, uveitis, nephrotic syndrome, immune suppression in transplantation, anaphylaxis, severe hypersensitivity reaction, dermatomyositis, mixed connective tissue disease, polyarteritis nodosa, bullous pemphigoid, ulcerative colitis, optic neuritis, autoimmune hemolytic anemia, idiopathic thrombocytopenic purpura, acute and lymphatic leukemia and malignant lymphoma.

    Product Features:
    Product Name Xalcort
    Generic Name Deflazacort
    Formulation Tablet & Suspension
    Available Pack Size 6 mg (60’s), 24 mg (30’s), 30 mg (10’s), 50 mL & 30 mL
    Available Strength 6 mg, 24 mg, 30 mg Tablet & 6 mg per 5 mL Suspension
    Registrations Bangladesh
       
  • Product Description: Renesis (Roxadustat) is a the first-in-class, oral tablet that promotes erythropoiesis through the endogenous production of erythropoietin (EPO) near physiological range. Upon administration, roxadustat binds to and inhibits HIF-PH (Prolyl Hyroxylase) , an enzyme responsible for the degradation of transcription factors in the HIF family under normal oxygen conditions. This prevents HIF breakdown and promotes HIF activity. Increased HIF activity leads to an increase in endogenous erythropoietin Production. It also upregulates the distribution, metabolism and absorption of iron within the body as well as downregulates hepcidin which is responsible for improper intracellular iron transportation. Therefore, Renesis (Roxadustat) can induce endogenous production of mature HB plump with iron. Renesis (Roxadustat) is indicated for treatment of adult patients with systematic anemia and functional iron deficiency anaemia associated with chronic kidney disease (CKD), Chemotherapy induced anemia and chronic disease induced anemia. Reneis (Roxadust) also improves hypo responsiveness of ESA in CKD patients. Product Features:
    Product Name Renesis
    Generic Name Roxadustat INN
    Formulation Oral Tablet
    Available Pack Size 3’s
    Available Strength 20 mg, 50 mg, 70mg & 100 mg
    Registrations Bangladesh